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Engineered oncolytic herpes virus inhibits ovarian and breast ...

http://feedproxy.google.com/~r/sciencedaily/top_news/top_health/~3/IZqPRKXO0hE/130201090820.htm?utm_source=feedburner&utm_medium=email
Feb 1, 2013 ... A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, ...

CA2687301C - Synthetic herpes simplex viruses type-1 for treatment ...

https://patents.google.com/patent/CA2687301C/en
Intratumor treatment with either OncSyn or OncdSyn virus caused a substantial reduction of tumor ... Herpes simplex virus 1 (HSV-1) for cancer treatment.

US8492443B2 - Treatment for herpes simplex virus and other ...

https://patents.google.com/patent/US8492443B2/en
Recently herpes virus was isolated from cardiac tissue. HSV 1 and HSV 2 infections pose very serious health threats often causing: blindness; increased cancer ...

‪Manuel Caruso‬ - ‪Google Scholar‬

https://scholar.google.com/citations?user=2gO6WsgAAAAJ&hl=en
... cause sterility in transgenic mice. B ... Gene therapy against cancer and HIV infection using the gene encoding herpes simplex virus thymidine kinase.

US20110033419A1 - Methods and Compositions for Treating Cancer

https://patents.google.com/patent/US20110033419A1/en
Oncolytic viruses act to reduce tumor burden by infecting tumors and causing cell death (Shen Y, Nemunaitis J. Herpes simplex virus 1 (HSV-1) for cancer ...

US20130202639A1 - Synthetic Herpes Simplex Viruses for ...

https://patents.google.com/patent/US20130202639
These exogenous genes can lead to expression of proteins that can, for example, inhibit HSV or cancer suppression of the immune response, present a specific ...

WO2017013419A1 - Use of oncolytic herpes simplex virus, alone or ...

https://patents.google.com/patent/WO2017013419A1/e
Cancer cells normally acquire antigenicity that can be recognised by the adaptive immune system as non-self and lead to generation of an immune response ...

US10821140B2 - Construction of oncolytic herpes simplex viruses ...

https://patents.google.com/patent/US10821140B2/en
The foreign genes cause the host to see the cancer cells as legitimate targets of adaptive immune response. The HSV-1 genome consists of two covalently linked ...

WO2013167909A1 - Herpes simplex virus for the treatment of liver ...

https://patents.google.com/patent/WO2013167909A1/en
It is thought to be the third most common cause of death due to cancer causing an estimated 662,500 deaths annually. Diagnosed HCC tripled in the period ...

US20160361374A1 - Use of a casein hydrolysate as an antiviral ...

https://patents.google.com/patent/US20160361374A1/en
Exceptionally, the reactivation or primary infection with herpes simplex virus can cause ... cancer, penile cancer and/or oropharyngeal cancer, caused by ...

WO2006063402A1 - Therapeutic compositions based on extracts of ...

https://patents.google.com/patent/WO2006063402A1/en
... cancers, inflammations and skin discolorations that are caused by a virus. ... herpes simplex virus 1; herpes simplex virus 2; and human papillomavirus. 13 ...

WO2012043710A1 - VECTEUR VIRAL À CROISSANCE RÉGULÉE ...

https://patents.google.com/patent/WO2012043710A1/fr
HSV herpes simplex virus; TK herpes simplex virus; SV40-derived ... Virus proteins cause cancer cell-specific cell death, and further proliferating viruses ...

US10328136B2 - Identification of mutations in herpes simplex virus ...

https://patents.google.com/patent/US10328136B2/en
... trigger the virus entry process in response to virus engagement of alternate receptors. ... Varghese et al., "Oncolytic herpes simplex virus vectors for cancer ...

US20170071991A1 - Oncolytic Virus and Aurora Kinase Inhibitor for ...

https://patents.google.com/patent/US20170071991A1/en
... cancer: causes and therapies. Nat Rev Cancer 1: 194 ... In some preferred embodiments the herpes simplex virus is HSV-1 strain 17 mutant 1716 (HSV1716).