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WT mice also received vehicle for 3 months (n=6). Ten mg/kg Compound A in ABCD1 KO mice induced significant reduction in brain C24:0 LPC (FIG. 3E) and in brain ...
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spA of at least 1×10 14 vg/kg or 3×10 14 vg/kg is effective to reduce serum AST, ALT, LDH, or total creatine kinase levels at 3 months or 6 months post ...
Tissue samples from the animals were analyzed for toxicological effects. The no adverse effect level in a three month toxicity study was 10 mg/kg in the rat and ...
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Nov 10, 2020 ... The CPAP group reduced their time in. AF from baseline to the last 3 months by 0.6 percentagepointsmorethanthecontrolgroup. (95% CI, 22.55 to ...
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Feb 20, 2022 ... The EQ-5D-3L was also administered every 3 months during survival follow-up. ... kg (n = 5), 8 mg/kg (n = 6), and 12 mg/kg (n = 6) in ...