Dec 13, 2021 ... An international team of scientists is hot on the trail of deciphering a key cause of one of the most common birth defects, thanks to a ...

Aug 3, 2022 ... "Ours is the first genetic study of coronary artery disease that had enough people of African and Hispanic descent to confirm previous findings ...

Jun 18, 2013 ... Coronary artery disease is the name given to the narrowing of blood vessels delivering blood to the heart, meaning that not enough oxygen can ...

Apr 27, 2022 ... ... and TBX5 -- interact with CHD4 inside the embryonic heart, recruit it for action, and uses CHD4 to play their roles in heart health and disease.

Oct 12, 2011 ... Jamie Engert, joint principal investigator of the study, who is a researcher in cardiovascular diseases at the Research Institute of the McGill ...

Apr 4, 2022 ... ... genetic testing is indicated for patients with inherited cardiac diseases and their relatives. We provide strict criteria on who should be ...

Jun 23, 2022 ... ... genetics methods to analyze if there is a link between certain DNA markers on RAP1GAP2 and heart disease. Her team will also use genetic ...

Dec 21, 2011 ... Diabetes is a major risk factor for cardiovascular disease and can reduce blood supply to the heart tissue and damage cardiac cells, resulting ...

Sep 21, 2022 ... Why this matters: Congenital heart disease is one of the leading causes of pediatric morbidity and mortality, which is why it is important to ...

Aug 27, 2022 ... ... their sights on curing forms of genetic heart disease using gene therapy. ... People of any age can fall victim to sudden heart failure and death, ...

Jul 12, 2022 ... Now officially in a Phase Ib clinical trial in New Zealand, VERVE-101 is a single base editor designed to permanently turn off the PCSK9 gene in ...

Feb 15, 2022 ... However, even though it is potentially the single most important gene for causing vascular disease, scientists around the world have little idea ...

Jun 23, 2022 ... ... are there cell populations or genes expressed that are different between health and disease? ... cardiac fibroblasts were found in some patients ...

May 16, 2012 ... Medical researchers explored naturally occurring genetic ... However, these individuals showed no difference in their risk of heart disease ...

Dec 19, 2013 ... ... their heart disease, the genetic trait was associated with a 38 percent increased risk of heart attack and death. "This finding requires ...

Aug 11, 2014 ... This is the start of a new clinical trial that will assess gene therapy for patients with heart pumps and provide detailed insight on its impact ...

In some embodiments, the promoter is a cardiac troponin T promoter (/. ., a TNNT2 promoter). In some embodiments, the rAAV vector genome comprises an expression ...

Dec 27, 2021 ... A diet rich in red meat correlates with increased risk for cardiovascular disease but the underlying genetic and biochemical mechanisms for ...

Sep 13, 2011 ... The Duke Clinical Research Institute is known for its work with patients who have cardiac/coronary disease and testing when it is best to employ ...

Sep 12, 2019 ... ... there is an unmet need ... 18, 2020 — Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure.