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US10570391B2 - RNAi agents, compositions and methods of use ...

https://patents.google.com/patent/US10570391B2/en
When the antisense strand is represented by formula (IIa), N b′ represents an oligonucleotide sequence comprising 0-10, 0-7, 0-10, 0-7, 0-5, 0-4, 0-2 or 0 ...

WO2015189597A1 - Priming of cancer cells with low dose ...

https://patents.google.com/patent/WO2015189597A1/en
cyclophosphamide may be administered at a dose (per administration) of up to 1800 mg/m 2 , for example 400- 1800mg/m 2 . the small molecule signalling inhibitor ...

Apple's iPhone Launch: A Case Study in Effective Marketing

https://groups.google.com/group/mbaoum0912-class2d/attach/2160f0f188d1652d/iPhone_2.pdf?part=0.1
AT&T offers the phones in its roughly 1,800 company-owned stores; iPhones are also available in ... (accessed February 13, 2008). Caulfield, B. 2008 ...

WO2007002433A1 - Pyrrolo [2, 3-b] pyridine derivatives as protein ...

https://patents.google.com/patent/WO2007002433A1/en
[0013] In some embodiments of any of the above embodiments of compounds of Formula Ia, each R 27 is independently optionally substituted cycloalkyl, optionally ...

WO2007024708A2 - Rna containing modified nucleosides and ...

https://patents.google.com/patent/WO2007024708A2/en
... 2A Human genes 0.000 description 2; 108010074922 Cytochrome P-450 CYP1A2 ... 1800 nucleotides. In another embodiment, the length is at least 2000 ...

WO2021035045A1 - Mettl16 inhibitors and uses thereof - Google ...

https://patents.google.com/patent/WO2021035045A1/en
In aspects, the METTL16 inhibitor is compound of Formula (I), (II), (III), (IV), (V), (VI), (VIA), (VIB), (VII), (VIIA), (VIII), (A), (B), (C), (D), (E), (F), ( ...

EP3700574A1 - Formulations of a compound modulating kinases ...

https://patents.google.com/patent/EP3700574A1/en
... 5C=C(F)C=CC=5)C4=CC=3)C2=C(C)C=1NC(=O)OC[C@@H]1COCCN1 LUJZZYWHBDHDQX ... 2-b]pyridin-3-yl)benzoic acid that inhibits bromodomain. US10428067B2 (en) ...

US9695233B2 - Bispecific anti-VEGF/anti-ANG-2 antibodies and ...

https://patents.google.com/patent/US9695233B2/de
US9695233B2 - Bispecific anti-VEGF/anti-ANG-2 antibodies and their use in the treatment of ocular vascular diseases - Google Patents.

US11060107B2 - Purification and purity assessment of RNA ...

https://patents.google.com/patent/US11060107B2/en
... 2-yl]methoxycarbonyl]benzoic acid Chemical compound C([C@]1(C)CC2=C3[C@@]([C@@]4(CC[C@H]5C(C)(C)[C@@H](OC(=O)C=6C(=CC=CC=6)C(O)=O)CC[C@]5(C)[C@H]4C=C3)C)(C ...

WO2018195165A1 - Methods for the treatment of subjects having a ...

https://patents.google.com/patent/WO2018195165A1/en
Subjects having chronic hepatitis B disease are HBsAg positive and ... P 2A, P 2B, P 3A, P 3B, P 4A, P 4B, P 5A, P 5B, P 5C, T 2A, T 2B, T 3A, T 3B ...

CA2702148C - Method of profiling gene expression in a human ...

https://patents.google.com/patent/CA2702148C/en
In the present invention, 20,000 ESTs have been produced from a human blood cell cDNA library and resulted in the identification of approximately 1,800 unique ...

Elementary Technical Mathematics 11Th Edition Pdf Answer Key ...

https://colab.research.google.com/drive/10dcWhm-VHNRhmeGmx4pRD8vrlBLsI9wS
... 2 3 3 12 4 7 1 2 4. 3 3 5 2 Cumulative Review 3 5 1 1 1 5. 1 3 6. 3 3 16 3 4 3 3 1. Find the prime factorization of 696. 16 5 7 2 11. 3 3 10 7 8 3 15 9 5 4 ...

WO2020069169A1 - Polynucleotides encoding arginase 1 for the ...

https://patents.google.com/patent/WO2020069169A1/en
... (b) (i) Compound VI, (ii). Cholesterol, and (iii) PEG-DMG or Compound I; (c) (i) ... Factor P (properdin) is a positive regulator of the alternative pathway.

WO2014138896A1 - Adaptive control technique for transmission ...

https://patents.google.com/patent/WO2014138896A1/en
Sep 18, 2014 ... -b nb a x a 2 ... a nJ is an identified parameter vector. [00139] For a fixed value of a t, the control algorithm becomes a special case of pole ...

WO2011071931A2 - Rna preparations comprising purified modified ...

https://patents.google.com/patent/WO2011071931A2/en
... 2A priority patent/CN102947450B/en: 2010-12-07 Priority to BR112012013875A ... 5C(C)(C)[C@@H](OC(=O)C=6C(=CC=CC=6)C(O)=O)CC[C@]5(C)[C@H]4C=C3)C)(C)CC[C ...

US8835108B2 - RNA containing modified nucleosides and methods ...

https://patents.google.com/patent/US8835108B2/en
... factor alpha Human genes 0.000 claims description 3; 208000022366 Pseudohypoaldosteronism type 2A Diseases 0.000 claims description 3; 102100032617 Pulmonary ...

US9399775B2 - RNAi agents, compositions and methods of use ...

https://patents.google.com/patent/US9399775B2/en
When the antisense strand is represented as formula (IIb), N b′ represents an oligonucleotide sequence comprising 0-10, 0-7, 0-10, 0-7, 0-5, 0-4, 0-2 or 0 ...

US9133461B2 - Compositions and methods for inhibiting ...

https://patents.google.com/patent/US9133461B2/en
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to ...

WO2017049245A2 - Compounds and compositions for intracellular ...

https://patents.google.com/patent/WO2017049245A2/en
... 5C(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)O[C@@H]4C)=O)C(C)C)=C3N=C21 ... prime untranslated region Proteins 0.000 description 2; GWEVSGVZZGPLCZ-UHFFFAOYSA ...

WO2021213945A1 - Coronavirus vaccine - Google Patents

https://patents.google.com/patent/WO2021213945A1/en
... positive B cells, and/or germinal center B cells. In some embodiments, a ... Plot of the ratio of pVNT 50 between SARS-CoV-2 lineage B.1.1.7 and Wuhan ...