... molecular adapter for capture and manipulation of transfer RNA. The adaptor is bound to a tRNA molecule. The adaptor may be a cholesterol-linked DNA adapter ...

... tRNA fMet molecules and eukaryotic systems initiator tRNA Met molecules. ... attached to the marker and to a truncated tRNA molecule. Linking groups may ...

Aug 26, 2013 ... ... transfer RNA molecules and attach the appropriate amino acids to those tRNAs. Once a tRNA is charged with its amino acid, it carries it to ...

By attaching the RNA molecules of this pool to the 5' end of a tRNA-like molecule and contacting the complex with a substrate molecule (natural or non-natural ...

Conventionally, each type of tRNA molecule can be attached to only one type of amino acid. The covalent attachment between the tRNAs and their specific ...

the amino acid added to the end to be elongated of the polypeptide chain is chosen by complementary base pairing between the anticodon of the tRNA molecule to ...

... tRNA within ternary complex. For sites more distal to the fluorophore linked to the tRNA molecule, multiple sites of labeling within EF-Tu could enable an ...

tRNA and the anticodon do not directly choose an amino acid, but an aminoacyl-tRNA synthetase (ARS) shows specificity to each amino acid, and each tRNA molecule ...

A biorecognition molecule is one which preferentially binds to another molecule. Biomolecular recognition molecules comprise aminoacyl-tRNA synthetases, tRNAs, ...

tRNAs are 73-93 nucleoside RNA molecules that recruit amino acid residues to the protein synthesis machinery. The structure of tRNA is often depicted as a ...

Aug 7, 2009 ... Small RNA molecules, called transfer RNAs (tRNAs), transport ... Each type of tRNA is attached to, or charged with, only one type of ...

... attached to the initiator tRNA. Polypeptides having an unnatural structure ... molecule capable of catalyzing tRNA acylation reaction. ARS ribozymes ...

[0071] During protein synthesis, a tRNA molecule delivers an amino acid to a ribosome for incorporation into a growing protein (polypeptide) chain. tRNAs ...

... attached to the editing domain of said tRNA synthetase. the tRNA synthetase is a member selected from a mitochondrial tRNA synthetase and a cytoplasmic tRNA ...

... attached to the marker and to a truncated tRNA molecule. Linking groups may be nucleotides, short oligonucleotides or other similar molecules and are ...

ADCs, for example, consist of a tumor antigen-specific antibody that is coupled to a chemotherapeutic small. molecule cytotoxin. Through targeted delivery of ...

Moiety refers to a radical of a molecule that is attached to the remainder of the molecule. ... For example, for leucyl tRNA synthetase, the cognate tRNA molecule ...

Jul 8, 2022 ... During aminoacylation, an amino acid attached to a given tRNA molecule is covalently attached to the 2' or 3' hydroxyl group of the 3 ...

[0011] Aminoacyl-tRNA synthetases (ARS) are a family of essential enzymes that attach amino acids to the 3' terminal adenosine end of tRNAs, the charged tRNAs ...

[0035] The term "preferentially aminoacylates" refers to the preference of a tRNA synthtase to aminoacylate (charge) a particular tRNA molecule with a ...